Looking to buy SS-31 peptide for laboratory research? Compare purity grades, COAs, storage, and typical SS-31 peptide dosing used in published studies.
SS-31 peptide, also known as elamipretide, is a synthetic mitochondria-targeted tetrapeptide sold strictly as a laboratory research chemical, not as a supplement or medicine. Anyone looking to buy SS-31 peptide should focus on three things: documented purity, batch-specific third-party testing, and a vendor that clearly labels the product for research use only. This guide covers what SS-31 is, how to evaluate suppliers, how it is handled in published studies, and how to store it correctly.
What SS-31 Peptide Is
The mitochondrial peptide ss-31 is a short chain of four amino acids (D-Arg-dimethylTyr-Lys-Phe-NH2) that concentrates in the inner mitochondrial membrane. It binds to cardiolipin, a phospholipid that helps organize the electron transport chain, and laboratory work suggests it can help stabilize that membrane under oxidative stress.
In the scientific literature the compound shows up under several names:
- Elamipretide — the clinical development name
- MTP-131 and Bendavia — earlier program names
- SS-31 — the original Szeto-Schiller designation
Published and ongoing research has examined elamipretide in heart failure, ischemia-reperfusion injury, Barth syndrome, dry age-related macular degeneration, and age-related mitochondrial decline. SS-31 peptide is not FDA-approved for human use in the United States and remains an investigational compound.
Why Purity and a Certificate of Analysis Matter
Research peptides are chemically synthesized, and the difference between a usable vial and a wasted experiment usually comes down to purity and handling. A reputable supplier provides a batch-specific certificate of analysis (COA) that you can match to the lot number printed on your vial.
When you review a COA, look for:
- HPLC purity of 98% or higher, with the chromatogram attached
- Mass spectrometry confirmation of the correct molecular weight
- Testing for residual solvents, heavy metals, and bacterial endotoxin
- Sterility testing if the product is supplied as a liquid
- A testing date and the name of an independent laboratory
A generic or undated COA that cannot be tied to your specific lot is a red flag. So is a vendor that refuses to share testing data before you pay.
How to Vet a Supplier When You Buy SS-31 Peptide
Because SS-31 is a research chemical, quality control is largely the buyer's responsibility. Working through a short checklist before ordering saves time, money, and repeat experiments.
Questions worth asking before checkout
- Does the listing say "for research use only" and avoid any human-use claims?
- Can the vendor send the exact COA for the lot currently in stock?
- Is the powder shipped at ambient temperature or on cold packs, and how fast does it arrive?
- Are bulk sizes available so a single lot can cover an entire study?
Domestic sourcing is often preferred for time-sensitive work, which is why many laboratories search for ss-31 peptide buy online usa options instead of importing. Ordering within the country shortens transit time, reduces customs risk, and makes replacements easier to resolve. If you are comparing suppliers and want to know where to buy ss-31 peptide from a vendor with verifiable testing, request the COA first and confirm the lot number before you check out.
Vial Sizes, Formats, and Typical Pricing
SS-31 is most commonly sold as a lyophilized (freeze-dried) powder in sealed glass vials. Liquid, pre-reconstituted versions exist, but they have a much shorter shelf life and are harder to ship safely.
| Format | Typical vial size | Reported purity | Approximate research price | Notes |
|---|---|---|---|---|
| Lyophilized powder | 5 mg | ≥98% HPLC | $40–$80 | Best for long-term storage |
| Lyophilized powder | 10 mg | ≥98% HPLC | $70–$140 | Common single-study size |
| Lyophilized powder | 50 mg | ≥98% HPLC | $280–$500 | Lower cost per milligram |
| Pre-reconstituted solution | 5–10 mg/mL | Varies | $60–$150 | Short shelf life, cold chain required |
| Bulk powder | 100 mg and up | ≥95–98% | Quoted per gram | Requires in-house testing |
Pricing shifts with lot size and supplier, so treat these figures as rough benchmarks rather than fixed rates. Cost per milligram drops sharply at larger vial sizes, but buying more than you can use before degradation is not a savings.
SS-31 Peptide Dosing in Published Research
Dosing information for SS-31 comes from animal models and from clinical trials of elamipretide, which used controlled administration under medical supervision. No self-administration protocol has been established, and SS-31 is not approved for human use.
What the literature reports:
- Preclinical rodent studies: roughly 1–5 mg/kg per day, usually given subcutaneously or intraperitoneally.
- Human infusion trials: 0.05–0.25 mg/kg per hour by intravenous infusion over several hours.
- Subcutaneous human trials: 40 mg once daily in Barth syndrome and dry AMD studies, with some protocols titrating upward from a lower starting amount.
Researchers planning a study often compare ss-31 peptide dosing across papers and find wide variation, because the amount depends on the model, the route, and the endpoint being measured. Any discussion of injection dosage therefore needs to reference a specific protocol rather than a single universal number.
Storage, Reconstitution, and Handling
Peptide degradation is usually a handling problem, not a manufacturing one. Basic lab practice preserves the material for the length of a study.
- Store lyophilized powder at -20 °C, protected from light and moisture.
- Let the vial reach room temperature before opening to prevent condensation.
- Reconstitute with bacteriostatic water or sterile saline, adding liquid down the vial wall rather than directly onto the powder.
- Refrigerate reconstituted solution at 2–8 °C and use it within about four weeks, or aliquot and freeze at -20 °C for longer storage.
- Avoid repeated freeze-thaw cycles, and discard any solution that looks cloudy or contains visible particles.
Legal and Safety Considerations
SS-31 peptide is sold as a research chemical and is not approved by the FDA for human use, so it cannot legally be marketed for human consumption in the United States. Buyers are responsible for complying with local, state, and federal regulations, including institutional rules at their facility.
Peptides sold for research are not manufactured under pharmaceutical good manufacturing practice, which means sterility and endotoxin content are not guaranteed for injectable human use. Anyone considering SS-31 for personal use should discuss it with a licensed healthcare professional rather than relying on vendor marketing. Researchers who also work with repair-oriented compounds apply the same documentation standard when they look into where to buy bpc-157 peptide.
Frequently Asked Questions
Can you buy SS-31 peptide legally in the US?
Yes, SS-31 peptide can be purchased legally in the United States as a laboratory research chemical. It is not FDA-approved for human use, so vendors may sell it only for research purposes and cannot market it as a drug, supplement, or treatment. Buyers are responsible for following applicable federal, state, and institutional rules.
What SS-31 peptide dosage do studies use?
Clinical trials of elamipretide have used intravenous infusions of roughly 0.05–0.25 mg/kg per hour and subcutaneous doses of 40 mg once daily. Preclinical animal studies typically use about 1–5 mg/kg per day. No human dose for self-administration has been established, and SS-31 is not approved for human use.
How should SS-31 peptide be stored after it arrives?
Lyophilized SS-31 powder should be stored at -20 °C, protected from light and moisture, where it remains stable for months. Once reconstituted, keep the solution refrigerated at 2–8 °C and use it within roughly four weeks, or aliquot and freeze it to avoid repeated freeze-thaw cycles.
This page provides educational research information and does not replace medical advice, diagnosis, or treatment.