CJC-1295 DAC 5mg is a research peptide vial. Learn what the DAC group does, how to reconstitute and store it, and how it compares with other peptides.
CJC-1295 DAC 5mg is a five-milligram vial of a synthetic growth hormone-releasing hormone (GHRH) analog that carries a Drug Affinity Complex (DAC) group. The DAC binds the peptide to albumin in the blood, stretching its half-life from minutes to roughly six to eight days. CJC-1295 DAC is sold strictly as a laboratory research chemical and is not FDA-approved for human use in the United States.
What the DAC Group Changes in CJC-1295
Plain CJC-1295, often labeled CJC-1295 without DAC or MOD GRF(1-29), clears from the body in about 30 minutes. The DAC version adds a maleimide linker that attaches to circulating albumin, which slows clearance dramatically.
- Half-life: roughly 30 minutes without DAC versus about 6–8 days with DAC.
- Exposure pattern: shorter-acting versions are studied with daily dosing, while the DAC version is studied with once- or twice-weekly exposure.
- Vial size: a 5 mg vial holds 5,000 micrograms (mcg) of lyophilized powder.
- Receptor activity: both forms act on pituitary GHRH receptors, but the DAC version produces a sustained release pattern rather than a sharp pulse.
A 5 mg vial of CJC-1295 DAC contains 5,000 mcg of peptide, which is 5 to 10 times the amount found in a typical 0.5–1 mg research vial.
How to Reconstitute CJC-1295 DAC 5mg
A 5 mg vial arrives as a freeze-dried cake and must be dissolved in bacteriostatic water before any lab work. Most cjc 1295 dac reconstitution guides recommend dripping the water slowly down the vial wall, then swirling gently — never shaking — until the powder dissolves completely.
Final concentration depends entirely on how much water you add. The table below shows how much peptide sits in a given volume.
| Bacteriostatic water added | Final concentration | Peptide per 0.1 mL |
|---|---|---|
| 1 mL | 5 mg/mL | 500 mcg |
| 2 mL | 2.5 mg/mL | 250 mcg |
| 5 mL | 1 mg/mL | 100 mcg |
Store lyophilized vials in a freezer at −20 °C or colder and keep them out of light. Once reconstituted, refrigerate the solution at 2–8 °C and use it within a few weeks. Repeated freeze-thaw cycles degrade the peptide and should be avoided.
Reported CJC-1295 DAC Dosage and Cycle Length
No regulatory agency has established a safe or effective human dose for CJC-1295 DAC. Anecdotal reports, including cjc 1295 dac dosage per week reddit discussions, cluster around 1–2 mg per week, usually split into two injections because of the long half-life.
- Common anecdotal range: 1–2 mg per week.
- Lower end cited online: 0.5–1 mg weekly, often described as a starting point.
- Typical cjc 1295 dac cycle length in user logs runs 8–12 weeks, followed by a break.
- Because the half-life is measured in days, unwanted effects cannot be cleared quickly by stopping a dose.
These numbers come from forum posts, not clinical trials, and should not be treated as medical guidance.
CJC-1295 With DAC vs Without DAC vs Ipamorelin
Researchers often compare cjc-1295 with dac vs ipamorelin when designing a protocol, because the two compounds act on different receptors. Ipamorelin is a selective ghrelin receptor agonist with a short half-life, while CJC-1295 DAC works through GHRH receptors with a week-long tail. Many suppliers sell cjc-1295 without dac 5mg ipamorelin 5mg as a paired research kit for exactly that reason.
| Peptide | Half-life | Receptor target | Typical research pairing |
|---|---|---|---|
| CJC-1295 with DAC | ~6–8 days | GHRH receptor | Used alone, once or twice weekly |
| CJC-1295 without DAC | ~30 minutes | GHRH receptor | Stacked with a ghrelin agonist 1–3 times daily |
| Ipamorelin | ~2 hours | Ghrelin / GHS-R1a | Stacked with a GHRH analog |
The DAC version is generally chosen when a long, steady signal is the research goal; the non-DAC version is chosen when pulsatile, short-lived release matters more. "Before and after" content posted on forums is personal anecdote, not controlled data, and cannot be used to judge whether any of these compounds work.
Safety, Sourcing, and Legal Status
CJC-1295 DAC is not approved for human use in the United States and is not a dietary supplement. Vials sold online are typically labeled "for research purposes only," which places handling, storage, and disposal responsibility on the buyer.
Side effects described in user reports include injection-site irritation, flushing, water retention, joint stiffness, and headaches. The extended half-life is the main safety concern: a reaction to a long-acting peptide cannot be reversed by simply skipping the next dose. Anyone considering any peptide for personal use should speak with a licensed healthcare professional first.
When evaluating a 5 mg vial, look for a third-party certificate of analysis showing purity above 98% by HPLC, a correct molecular mass by mass spectrometry, and no endotoxin contamination. A cheap vial with no documentation is a poor research material and a possible health risk.
Frequently Asked Questions
What is CJC-1295 DAC 5mg used for?
In laboratory settings it is used as a long-acting GHRH analog to study growth hormone signaling and receptor activity. It is not FDA-approved for human use, and no clinical trial has established a safe or effective human dose. Online reports about body composition or recovery are anecdotal and unverified.
How much bacteriostatic water do you add to a 5mg CJC-1295 DAC vial?
Most reconstitution guides use 1–2 mL of bacteriostatic water, which produces a concentration of 5 mg/mL or 2.5 mg/mL. Adding 2 mL is common because it makes small volumes easier to measure accurately. Store the reconstituted solution refrigerated at 2–8 °C and avoid repeated freeze-thaw cycles.
How often is CJC-1295 DAC injected in reported protocols?
Because the DAC group extends the half-life to roughly 6–8 days, anecdotal protocols typically use it once or twice per week, unlike the non-DAC version that is used daily. These schedules come from user forums rather than clinical research. There is no approved human dosing schedule, so a healthcare professional should be consulted before any personal use.
This page provides educational research information and does not replace medical advice, diagnosis, or treatment.