Custom peptide synthesis GenScript offers researchers fast quotes, purity options up to 98%, and scales from milligrams to grams. Learn how it works.
GenScript custom peptide synthesis is a made-to-order service that produces synthetic peptides for laboratory research, typically at purities between 70% and 98%+ and scales from a few milligrams to multi-gram batches. You submit an amino acid sequence, choose purity, quantity, and any modifications, and GenScript returns a lyophilized peptide with a certificate of analysis. GenScript peptides are sold for research use only and are not intended for human or veterinary use.
Most labs turn to a custom peptide synthesis service when they need a specific sequence that is not available off the shelf. Peptides commonly run from about 5 to 50 residues, though longer and more difficult sequences are possible after a feasibility review. The real value of the service is not only the molecule, it is the documentation that confirms what was actually made.
What GenScript Custom Peptide Synthesis Covers
GenScript handles routine linear peptides as well as many difficult chemistries. Most projects combine several of the options below.
- Sequence range: short peptides through long, hydrophobic, or aggregation-prone sequences that need special handling.
- Purity tiers: crude, desalted, and HPLC-purified grades at roughly 70%, 80%, 90%, 95%, and 98%+.
- Modifications: biotinylation, phosphorylation, acetylation, amidation, cyclization, D-amino acids, and fluorescent labels such as FITC and FAM.
- Carrier conjugation: KLH, BSA, and OVA conjugates used to raise antibodies.
- Library formats: peptide libraries, alanine scanning sets, scrambled controls, and epitope mapping panels.
How the Ordering Process Works
Every sequence is quoted individually because length, purity, quantity, and modifications all change the price. A 10-mer at 70% purity and a 45-mer carrying two fluorescent tags are not comparable jobs.
- Submit the sequence and specifications. Online ordering tools flag problematic sequences before synthesis begins.
- Receive a feasibility review and quote. The quote confirms length, purity grade, scale, modifications, and an estimated turnaround.
- Synthesis and purification. Peptides are built by solid-phase synthesis, then cleaved and purified to the grade you selected.
- Quality control. HPLC and mass spectrometry verify purity and molecular weight.
- Delivery. The peptide arrives lyophilized with a certificate of analysis and storage instructions.
Purity, Scale, and Price at a Glance
Purity is the single biggest driver of cost after sequence length. Higher purity means more material is lost during purification, so the price per milligram climbs quickly.
| Purity grade | Typical research use | Relative cost |
|---|---|---|
| Crude or desalted | Screening, non-critical assays, optimization runs | Lowest |
| 70-80% | ELISA coating, preliminary binding studies | Low |
| 90-95% | Cell assays, receptor binding, most immunology work | Moderate |
| 98%+ | Structural studies, sensitive assays, animal research | Highest |
Scale follows the same logic. Ordering 1 mg costs far more per milligram than ordering 10 mg, but buying more peptide than an assay needs wastes both budget and shelf life.
How GenScript Compares With Other Peptide Suppliers
Custom Peptide Synthesis pricing is rarely apples-to-apples, because vendors quote different purities, scales, and QC packages. GenScript is generally strongest on high-throughput orders, broad modification menus, and workflows that combine gene synthesis with peptide work.
| Supplier type | Where it tends to fit best |
|---|---|
| GenScript | High-throughput custom orders, gene-to-protein projects, wide modification catalog |
| Sigma-Aldrich / Merck | Catalog peptides plus custom quotes through a familiar academic distribution channel |
| Bachem and similar specialists | Large-scale and GMP-track peptides for regulated development programs |
| Academic core facilities | Low-cost simple sequences, with variable turnaround and limited QC depth |
Labs that weigh sigma custom peptide synthesis against GenScript usually base the decision on turnaround time, documentation depth, and how much sequence difficulty a vendor will accept without surcharges.
Regional Availability, Shipping, and Customs
GenScript ships internationally, and regional suppliers are worth comparing when local turnaround or import paperwork matters. Researchers in the UK and EU often weigh custom peptide synthesis uk and custom peptide synthesis europe options against US-based suppliers on lead time, VAT, and customs handling.
Groups in India, China, and Australia typically evaluate domestic vendors for the same reasons: shorter shipping, easier replacement if a QC failure occurs, and procurement rules that favor local invoicing. Sequence quality across established vendors is broadly comparable, so logistics often decide the order.
Quality Control, Safety, and Research-Use-Only Rules
GenScript supplies HPLC traces and mass spectrometry data with each peptide, and purity is reported as the percentage of the target peak. That paperwork matters when results need to be reproduced or published.
These products are research-use-only reagents. They are not FDA-approved drugs, foods, or supplements, and they are not produced under GMP conditions unless a project is specifically set up that way. Anyone considering a peptide for a health condition should consult a licensed healthcare professional rather than self-experiment with research-grade material.
For most academic and biotech labs, the practical checklist is simple: match purity to the assay, confirm the modification chemistry, and keep the certificate of analysis on file with your data.
Frequently Asked Questions
Is GenScript custom peptide synthesis FDA approved?
No. The FDA does not approve peptide synthesis services, and GenScript peptides are research-use-only reagents rather than approved drugs or supplements. A peptide would only become an FDA-approved product after its own clinical development and regulatory review.
How long does GenScript custom peptide synthesis take?
Turnaround usually ranges from a few business days for short, standard sequences to several weeks for long, heavily modified, or 98%+ purified peptides. Express options can shorten standard timelines, and quotes include an estimated delivery window. Library orders and difficult chemistries are the most likely to run longer.
How much does custom peptide synthesis cost at GenScript?
GenScript quotes each sequence individually because price depends on length, purity grade, quantity, and modifications. Short crude or desalted peptides cost the least, while long sequences with fluorescent labels and 98% purification cost substantially more per milligram. Requesting several purity tiers in one quote makes comparison easier.
This page provides educational research information and does not replace medical advice, diagnosis, or treatment.