A complete dosage chart for semaglutide for weight loss and diabetes: weekly titration from 0.25 mg to 2.4 mg, unit conversions, and safety tips.
Semaglutide dosing follows a standard stepped schedule in the United States: 0.25 mg once weekly for 4 weeks, then 0.5 mg, 1 mg, 1.7 mg, and a maintenance dose of 2.4 mg for weight loss (Wegovy) or up to 2 mg for type 2 diabetes (Ozempic). A dosage chart for semaglutide simply maps each dose to a week number and, for compounded vials, to a volume in milliliters or units on an insulin syringe. Your prescriber sets the actual plan, and the titration pace can vary based on side effects, response, and the specific product you receive.
Standard Semaglutide Dosage Chart by Week
Branded pens use a fixed, four-week step-up. The starting dose is intentionally low so the body can adjust before the dose increases.
| Weeks | Dose (mg) | Typical purpose |
|---|---|---|
| 1–4 | 0.25 mg | Starting dose; not expected to drive weight loss on its own |
| 5–8 | 0.5 mg | First step-up; appetite effects often begin here |
| 9–12 | 1 mg | Common maintenance level for type 2 diabetes |
| 13–16 | 1.7 mg | Wegovy step-up toward weight-loss maintenance |
| 17+ | 2.4 mg (Wegovy) or up to 2 mg (Ozempic) | Maintenance, adjusted by your clinician |
Wegovy maintenance is 2.4 mg weekly, and some patients remain at 1.7 mg if side effects limit further increases. Ozempic for diabetes typically tops out at 2 mg weekly. Neither brand recommends skipping the titration steps.
Semaglutide Dosing Chart in Units (Compounded Vials)
Units are not a dose — they are a volume. One unit on a U-100 insulin syringe equals 0.01 mL, so the number of units depends entirely on the concentration of the vial in front of you. A 5 mg/mL vial and a 10 mg/mL vial can deliver the same milligram dose in very different unit counts.
Many patients look for a semaglutide 5mg/ml dosage chart because that concentration is common at compounding pharmacies. The math is straightforward: divide the milligram dose by the concentration to get milliliters, then multiply by 100 to convert to units.
| Dose (mg) | Volume at 5 mg/mL | Units on U-100 syringe |
|---|---|---|
| 0.25 mg | 0.05 mL | 5 units |
| 0.5 mg | 0.1 mL | 10 units |
| 1 mg | 0.2 mL | 20 units |
| 1.7 mg | 0.34 mL | 34 units |
| 2.4 mg | 0.48 mL | 48 units |
If you are holding a semaglutide 5mg 2ml dosage chart scenario — 5 mg of drug inside a 2 mL vial — the concentration is actually 2.5 mg/mL, which roughly doubles every unit count above. Read the label every time, because guessing here is how dosing errors happen.
Brand, Telehealth, and Compounded Charts Compared
Telehealth programs publish their own titration tables. A hers semaglutide dosage chart, for example, generally starts at 0.25 mg and advances in similar four-week blocks, but the delivery format — prefilled pen versus vial and syringe — changes how you measure each dose.
Some compounded formulas add cyanocobalamin (vitamin B12). A semaglutide cyanocobalamin dosage chart lists the same semaglutide milligrams but a different total volume, because the B12 adds liquid. Never apply a plain semaglutide chart to a B12-blended vial without confirming the concentration on the pharmacy label.
| Format | How it is measured | Where the chart comes from |
|---|---|---|
| Branded pen (Wegovy, Ozempic) | Click or dial count on the pen | Manufacturer prescribing information |
| Telehealth compounded vial | Units on a U-100 syringe | The dispensing pharmacy or program |
| B12-blended compounded vial | Units, adjusting for added volume | Pharmacy label plus prescriber instructions |
Reading a Semaglutide Weight Loss Dosage Chart in Units
When people search for a semaglutide weight loss dosage chart units version, they usually want to know how many units to draw at each titration step. Units only make sense next to a specific concentration.
- 0.25 mg from a 5 mg/mL vial: 5 units
- 0.5 mg from a 5 mg/mL vial: 10 units
- 1 mg from a 5 mg/mL vial: 20 units
- 1.7 mg from a 5 mg/mL vial: 34 units
- 2.4 mg from a 5 mg/mL vial: 48 units
At 2.5 mg/mL those numbers roughly double; at 10 mg/mL they roughly halve. Confirm the concentration and the syringe size with your pharmacist before your first injection.
Don't Confuse Semaglutide Charts With Other Peptide Charts
Search results often mix GLP-1 dosing with research-peptide dosing. A bpc-157 dosage chart by weight, for instance, describes a completely different compound studied in tissue-repair models, not appetite regulation. In the same way, an aod 9604 dosage for men schedule has nothing to do with semaglutide titration, even when the same vendor sells both.
Semaglutide is a prescription GLP-1 receptor agonist. Research peptides labeled for laboratory use only are not FDA-approved for human consumption, and a semaglutide peptide dosage chart circulating on a forum is not a substitute for a prescription. Compounded semaglutide is also not FDA-approved, and the FDA has issued warnings about dosing errors tied to unfamiliar concentrations.
Safety Notes Before You Titrate
- Increase slowly. Move up no more often than every four weeks unless a clinician directs otherwise.
- Expect common effects. Nausea, vomiting, diarrhea, and constipation are the most frequent complaints, especially after a step-up.
- Know the red flags. Severe or persistent abdominal pain, unrelenting vomiting, and gallbladder symptoms need medical attention.
- Do not double up. If you miss a dose, follow your prescriber's instructions instead of taking two doses at once.
- Skip it in pregnancy. GLP-1 medications are not recommended during pregnancy or breastfeeding.
Talk with a licensed healthcare professional before starting, stopping, or changing any semaglutide dose. Bring your vial, pen, and syringe to the appointment so the numbers on the chart can be matched to the numbers on your label.
Frequently Asked Questions
What is the starting dose of semaglutide?
The standard starting dose is 0.25 mg once weekly for four weeks. That dose is meant for tolerability, not weight loss, and it is followed by 0.5 mg for the next four weeks if it is tolerated well.
How many units is 1 mg of semaglutide?
It depends entirely on the concentration of your vial. At 5 mg/mL, 1 mg equals 0.2 mL, or 20 units on a U-100 syringe. At 2.5 mg/mL, the same 1 mg dose equals 40 units.
Does Hers use the same semaglutide dosage chart?
Hers and similar telehealth programs generally follow the same 0.25 mg to 2.4 mg titration, but the format they ship, such as a compounded vial and syringe, determines how you measure each dose. Always follow the specific chart included with your prescription.
This page provides educational research information and does not replace medical advice, diagnosis, or treatment.