Epitalon 50mg Vial: What Researchers Should Know

An Epitalon 50mg vial is a sealed, lyophilized container holding 50 milligrams of the synthetic tetrapeptide Epitalon (also spelled epithalon). It is manufactured and sold strictly for laboratory research, not for human or veterinary use, and 50mg is a large format compared with the more common 10mg vial. Researchers choose the 50mg size when a study needs many aliquots drawn from one consistent lot.

What Is Epitalon and Why Do Labs Study It?

Epitalon is a short tetrapeptide with the sequence Ala-Glu-Asp-Gly. It was designed as a synthetic analog of epithalamin, a peptide fraction extracted from the pineal gland.

Most published work examines effects on telomerase activity, cell proliferation, and circadian markers in cultured cells and animal models. These are early-stage laboratory findings, not proven treatments for any human condition.

Epitalon is not FDA-approved for human use in the United States. It appears in research chemical catalogs rather than licensed pharmacies, and its label typically reads "for research use only."

Epitalon 50mg vs 10mg vs 20mg Vials

Vial size determines how much diluent you need and how many working aliquots one container supports. The table below compares the formats suppliers most often stock.

Vial Size	Powder Mass	Common Reconstitution Volume	Resulting Concentration	Typical Research Use
10mg	10 mg Epitalon	2 mL	5 mg/mL	Small pilot assays, single-operator labs
20mg	20 mg Epitalon	4 mL	5 mg/mL	Mid-size experiments, short protocols
50mg	50 mg Epitalon	10 mL	5 mg/mL	Long protocols, multi-arm studies, lot consistency

A 50mg vial cuts down on freeze-thaw cycles and lot changes, which matters when an experiment runs for weeks. It usually lowers the cost per milligram as well. When you compare listings of epitalon for sale, confirm that the certificate of analysis reports purity by HPLC and identity by mass spectrometry.

Epitalon Peptide Reconstitution: Step by Step

The math behind epitalon peptide reconstitution controls every downstream measurement, so measure carefully and label everything.

1. Let the vial and the diluent reach room temperature.
2. Swab the stopper with 70% isopropyl alcohol and allow it to dry.
3. Draw sterile or bacteriostatic water into a syringe and aim the stream at the glass wall, not directly at the powder.
4. Swirl gently until the powder dissolves completely. Do not shake or vortex, which can shear the peptide.
5. Write the date, final concentration, and your initials on the label.

The core equation is simple: milligrams of powder divided by milliliters of water equals concentration.

Water Added to a 50mg Vial	Concentration	Volume Needed for a 5mg Research Amount
5 mL	10 mg/mL	0.5 mL
10 mL	5 mg/mL	1.0 mL
25 mL	2 mg/mL	2.5 mL

Keep lyophilized powder frozen at -20°C and protected from light. Once reconstituted, store the vial at 2-8°C and use it within the window your protocol specifies.

Epitalon Half-Life and Research Timing

In plasma, epitalon half life is short. Pharmacokinetic data on similar short peptides point to rapid enzymatic breakdown, with most of the parent compound cleared within minutes to a few hours.

That brief window is why animal studies tend to use repeated administrations or daily schedules instead of a single exposure. Protocols published in the literature often use milligram-level amounts in rodents, but no validated human dose exists.

Record exact concentrations, routes, and timing so another lab can replicate your results. Animal data should never be converted into human dosing instructions.

The Thymalin Epitalon Combination in Research

The combination known as thymalin epitalon appears in older Russian-language studies on immune and endocrine aging markers. Thymalin is a polypeptide fraction derived from calf thymus, while Epitalon is the synthetic pineal tetrapeptide.

Researchers pair them because they touch different regulatory systems: thymic immune signaling and pineal circadian signaling. Those findings remain preliminary and have not been confirmed by large, independent human trials.

Any protocol marketed as epitalon peptide therapy is experimental. No regulatory agency has approved Epitalon as a drug, and clinics selling it for anti-aging purposes operate outside standard approval pathways.

Safety, Storage, and Legal Considerations

• Epitalon is a research chemical and is not approved for human consumption in the US.
• Handle powder and solution with gloves, a lab coat, and eye protection, and avoid inhaling the powder.
• Store lyophilized vials frozen and dry; refrigerate reconstituted solution.
• Discard any vial showing cloudiness, particles, or discoloration.
• Anyone weighing peptide therapy for a health concern should speak with a licensed healthcare professional first.

Supply quality varies widely. Purchase only from vendors that publish third-party HPLC and mass spectrometry results tied to the exact lot number printed on your vial.

COMMON QUESTIONS

Frequently Asked Questions

How do I reconstitute an Epitalon 50mg vial?

Add sterile or bacteriostatic water slowly down the inside wall of the vial, then swirl gently until the powder dissolves. Adding 10 mL gives a 5 mg/mL solution, while adding 5 mL gives 10 mg/mL. Never shake the vial, and store the reconstituted solution at 2-8°C.

Is Epitalon legal to buy in the US?

Epitalon is sold as a research chemical, not as an approved drug. Purchasing it for laboratory research is legal in most US states, but it is not FDA-approved for human consumption. Check your state and institutional rules before ordering.

How long does a 50mg Epitalon vial last?

Lyophilized powder stored at -20°C can remain stable for months to a couple of years, depending on the supplier's stability data. Once reconstituted with bacteriostatic water, most labs use the solution within 2 to 4 weeks while refrigerated. Always follow the storage instructions on the certificate of analysis.