Hims Semaglutide Dosage Chart: How the Weekly Titration Works

Hims & Hers has offered semaglutide through affiliated pharmacies, and its dosing schedule follows the same step-up pattern used by brand-name GLP-1 medications: 0.25 mg once weekly for four weeks, then 0.5 mg, 1 mg, 1.7 mg, and up to 2.4 mg weekly, with most steps lasting about four weeks. There is no single public "Hims dosage chart," because the number printed on your label is set by your prescriber and by the concentration the pharmacy ships. This guide explains how that chart is built, how milligrams translate into syringe units, and what to confirm before your first injection.

Typical Hims semaglutide titration schedule

Semaglutide is started low and raised slowly so the body can adjust. Moving up too fast is the most common reason people get severe nausea and vomiting.

Weeks	Weekly dose	What it means
1–4	0.25 mg	Starter dose; not intended to drive weight loss on its own
5–8	0.5 mg	First increase if side effects are tolerable
9–12	1 mg	Common maintenance range for many patients
13–16	1.7 mg	Intermediate step toward the maximum
17 and beyond	2.4 mg	Highest weekly dose studied for weight management

Not everyone reaches 2.4 mg. Providers sometimes hold a patient at 1 mg or 1.7 mg when results are on track, and some patients stay at 0.5 mg because of side effects.

Reading the chart: milligrams versus units

Compounded semaglutide often arrives as a vial plus an insulin-style syringe marked in units rather than milligrams. That is why a dosage chart for semaglutide can look confusing: the same milligram dose equals a different number of units depending on the vial's concentration.

On a standard U-100 syringe, 1 mL equals 100 units. Here is how the standard titration converts at two common concentrations.

Weekly dose	Units at 5 mg/mL	Units at 2.5 mg/mL
0.25 mg	5 units	10 units
0.5 mg	10 units	20 units
1 mg	20 units	40 units
1.7 mg	34 units	68 units
2.4 mg	48 units	96 units

A vial labeled 5 mg/2 mL is the same strength as 2.5 mg/mL, so a semaglutide 5mg 2ml dosage chart should line up with the right-hand column above. Always verify the concentration printed on your own vial instead of copying numbers from someone else's prescription.

Why your chart may differ from someone else's

• Concentration: A semaglutide 5mg/ml dosage chart gives different unit numbers than a 10 mg/mL vial for the same milligram dose.
• Titration speed: Providers vary in how long they keep you at each step before increasing.
• Formulation: Tablets, prefilled pens, and compounded vials are all measured differently.
• Tolerance: Side effects, not the calendar, often decide when the next increase happens.

Some pharmacies use higher-concentration vials to reduce injection volume. A semaglutide 10mg dosage chart may show only a few units for a dose that takes much more volume in a weaker vial.

Compounded versus brand-name semaglutide

Option	How it is measured	Typical maintenance dose
Compounded semaglutide vial	Syringe units based on concentration	Varies by prescriber, often 1–2.4 mg weekly
Wegovy (FDA-approved)	Single-dose pen, dose printed on the pen	Up to 2.4 mg weekly
Ozempic (FDA-approved for type 2 diabetes)	Pen with dial-a-dose	0.5–2 mg weekly

Brand-name products deliver the dose for you, so there are no units to calculate. Compounded vials require you to draw the dose yourself, which adds room for error. If you look up a semaglutide weight loss dosage chart units version, check that the source states which concentration it assumes.

Compounded semaglutide is not FDA-approved for human use in the United States. The FDA has warned that compounded versions may differ in strength, purity, or the form of the active ingredient, and Hims & Hers' semaglutide offering has shifted as federal shortage rules changed, so confirm what is currently available before assuming a chart applies to you.

Side effects to watch for

• Nausea, vomiting, diarrhea, or constipation — most common in the weeks after each dose increase.
• Heartburn, bloating, burping, and reduced appetite.
• Rare but serious: pancreatitis, gallbladder disease, severe dehydration, and kidney injury.
• Boxed warning: thyroid C-cell tumors seen in rodents; not recommended for people with a personal or family history of medullary thyroid carcinoma or MEN2.

Severe or persistent abdominal pain, signs of dehydration, or vision changes warrant prompt medical attention. Do not raise your dose on your own to speed up results.

Questions to ask your prescriber

1. What concentration is my vial, and how many units equal my dose?
2. How long should I stay at this dose before increasing?
3. Which side effects mean I should pause and call you?
4. Would an FDA-approved product be a better fit for me than a compounded one?

Community threads — the kind you would find in a semaglutide 5mg ml dosage chart reddit discussion — can offer perspective but are not a dosing reference. Misreading a concentration is a common cause of accidental double doses, so your label always wins.

COMMON QUESTIONS

Frequently Asked Questions

What is the starting dose of Hims semaglutide?

Most semaglutide prescriptions, including those filled through Hims-affiliated pharmacies, begin at 0.25 mg once weekly for four weeks before moving to 0.5 mg. Your prescriber sets the exact starting dose and schedule based on your health history and the concentration the pharmacy ships. The starter dose is for tolerability, not weight loss.

How many units is 0.25 mg of semaglutide in a 5 mg/mL vial?

In a 5 mg/mL vial, 0.25 mg equals 5 units on a U-100 insulin syringe (0.05 mL). In a 2.5 mg/mL vial, the same dose equals 10 units. Always check the concentration on your own label, because unit numbers change whenever the concentration changes.

Is compounded semaglutide from Hims FDA-approved?

No. Compounded semaglutide is not FDA-approved for human use in the United States, and the FDA has warned about dosing errors, impurities, and different forms of the active ingredient in compounded products. FDA-approved options such as Wegovy and Ozempic require a prescription and come in pens that deliver a fixed dose.